

Similarly, a Nordic-type diet can modulate the blood lipid profile of hypercholesterolemics. In this context, a portfolio of vegetarian foods has been shown capable of improving LDL cholesterol, HDL cholesterol and CRP values in hypercholesterolemic subjects. These guidelines focus on lowering LDL cholesterol, fasting glycemia, body weight and blood pressure as a way to reduce the risk of heart disease. Current recommendations for dietary management of subjects with high metabolic risk involve quantitative and qualitative changes in fat and sugar intakes and high consumption of fruits, vegetables, and whole grains. Therefore, any person with multiple cardiometabolic risk factors would benefit from lifestyle changes, including improvement of dietary habits, to favorably modify as many as possible risk-associated features. cardiovascular disease and diabetes mellitus, are important causes of morbidity and mortality worldwide. The improved biomarker levels recorded in healthy individuals following the multifunctional regime suggest preventive potential of this dietary approach against CMD.Ĭardiometabolic diseases (CMD), i.e. After AD, the Framingham cardiovascular risk estimate was 30 ± 4% ( P < 0.0001) lower and the Reynolds cardiovascular risk score, which considers CRP values, decreased by 35 ± 3% ( P < 0.0001). The differences remained significant after adjustment for weight change.

CD did not modify the metabolic variables measured. ResultsĪlthough the aim was to improve metabolic markers without promoting body weight loss, minor weight reductions were observed with both diets (0.9-1.8 ± 0.2% P < 0.05). AD included the following functional concepts: low glycemic impact meals, antioxidant-rich foods, oily fish as source of long-chain omega-3 fatty acids, viscous dietary fibers, soybean and whole barley kernel products, almonds, stanols and a probiotic strain ( Lactobacillus plantarum Heal19/DSM15313).

Each diet was consumed during 4 wk with a 4 wk washout period. Methodsįourty-four healthy women and men (50-73 y.o, BMI 25-33, fasting glycemia ≤ 6.1 mmol/L) participated in a randomized crossover intervention comparing a multifunctional (active) diet (AD) with a control diet (CD) devoid of the "active" components. The objective of this study was to assess, in healthy overweight individuals, the impact of a diet combining multiple functional concepts on risk markers associated with cardiometabolic diseases (CMD). Different foods can modulate cardiometabolic risk factors in persons already affected by metabolic alterations.
